I would propose a Zebrafish meeting Workshop on emerging Gene Knockout technology. My lab and at least two other labs are using engineered Zinc Finger Nucleases to perform targeted gene knock out and eventually gene knock-in in zebrafish, and it would be good to compare the various things we’ve tried, as well as other related technologies.
Regards,
Joe
*****
H. Joseph Yost, Ph.D.
Professor of Neurobiology & Anatomy
University of Utah School of Medicine
Eccles Institute of Human Genetics
Bldg. 533, Room 3160
15 North 2030 East
Salt Lake City, UT 84112-5330
Thursday, January 10, 2008
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3 comments:
I hope this would include a discussion of the use of vector based RNAi for producing germline knockouts of specific genes. One advantage of the vector based RNAi would be the ability to knockout multiple genes at a time.
Henry G. Tomasiewicz
NIEHS Marine and Freshwater BioMed Sci Ctr
University of Wisconsin-Milwaukee
Great Lakes WATER Insitute
This is an important discussion topic that I would like to see discussed.
Important topic that will be of interest to many. It would be good to also include a discussion of the status of zebrafish ES cells.
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